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Phylogeography of Ordovician-Silurian rhynchonelliformean brachiopods: tracking higher order distributional patterns, radiations and extinctions in 4D
Based on a large data-set, spanning the Ordovician-Early Silurian (Telychian) interval, this study explores the phylogeographic distributional pattern for higher orders of rhynchonelliformean brachiopods through four time slices: Tremadocian, Dapingian-Darriwilian, Katian and Telychian. In addition, a palaeobathymetrical analysis has been conducted for the latter two time slices to assess the phyl
Exhaled Breath Temperature in Asthmatics and Controls after Eucapnic Voluntary Hyperventilation and a Methacholine Challenge Test.
Background: It has been suggested that exhaled breath temperature (EBT) is increased in asthmatic subjects. Objectives: Our aim was to investigate EBT in asthmatics compared to healthy controls before and after eucapnic voluntary hyperventilation (EVH) and a methacholine challenge test (MCT). Methods: A total of 26 asthmatics and 29 healthy controls were included. Forced expiratory volume in 1 s (
Outcome measures in haemophilia: a systematic review
Haemophilia A and B are hereditary X-linked disorders due to deficiency (or absence) of coagulation factor VIII or IX, respectively. Bleeding risk is related to the severity of factor deficiency. Repeated joint bleeding can lead to a severe haemophilic arthropathy resulting in disabilities. Outcome measurements in persons with haemophilia (PWH) have been limited to laboratory evaluation (factor VI
Observation of anisotropic diffusion of light in compacted granular porous materials
By analyzing spatio-temporal characteristics of short optical pulses diffusively transmitted through compacted granular materials, we reveal that powder compaction can give rise to strongly anisotropic light diffusion. Our disclosure represents a revision of the understanding of optics of powder compacts. Routes to material characterization and investigation of compression-induced structural aniso
Longitudinal strain from velocity encoded cardiovascular magnetic resonance: a validation study
Background: Regional myocardial function is typically evaluated by visual assessment by experienced users, or by methods requiring substantial post processing time. Visual assessment is subjective and not quantitative. Therefore, the purpose of this study is to develop and validate a simple method to derive quantitative measures of regional wall function from velocity encoded Cardiovascular Magnet
The economics of slavery in eighteenth century Cape Colony: Revising the Nieboer-Domar hypothesis
The Nieboer-Domar hypothesis has proved to be a powerful tool for identifying the economic conditions under which slavery was more likely to emerge as a dominant form of labour. It states that in cases of land abundance and labour shortages the use of slavery was likely to become a vital alternative means of increasing production. These conditions have been identified for large parts of pre-coloni
Boronic Acid Terminated Thermo-Responsive and Fluorogenic Polymer: Controlling Polymer Architecture for Chemical Sensing and Affinity Separation
Thermo-responsive poly(N-isopropylacrylamide) (polyNIPAm) containing terminal boronic acid was synthesized using atom transfer radical polymerization (ATRP) in combination with Cu(I)-catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC) reaction. Alkyne-terminated polyNIPAm was first synthesized by ATRP using an alkyne-containing initiator. A fluorogenic boronic acid, 3-(2-azido-acetylamino)phe
The Finnefjeld domain, Maniitsoq structure, West Greenland: Differential rheological features and mechanical homogenisation in response to impacting?
The 35 by 50 km large, Mesoarchaean Finnefjeld domain near Maniitsoq in the North Atlantic craton of southern West Greenland constitutes the central part of the previously proposed, deeply eroded Maniitsoq impact structure with an age of 3.0 Ga. The Finnefjeld domain is an exceedingly homogeneous, quartzo-feldspathic rock mass which superficially appears to be a late-orogenic, deep-crustal, intrus
Associations between the angiotensin-converting enzyme insertion/deletion polymorphism and monoamine metabolite concentrations in cerebrospinal fluid
Angiotensin II has been suggested to influence central dopamine and serotonin turnover. Since the angiotensin-converting enzyme (ACE) plays a key role in angiotensin regulation by converting inactive angiotensin 1 to active angiotensin II, we hypothesised that the functional insertion/deletion (I/D) polymorphism in the ACE gene, which has previously been suggested to be associated with, depression
Weak Self-Interactions of Globular Proteins Studied by Small-Angle X-ray Scattering and Structure-Based Modeling.
We investigate protein-protein interactions in solution by small-angle X-ray scattering (SAXS) and theoretical modeling. The structure factor for solutions of bovine pancreatic trypsin inhibitor (BPTI), myoglobin (Mb), and intestinal fatty acid-binding protein (IFABP) is determined from SAXS measurements at multiple concentrations, from Monte Carlo simulations with a coarse-grained structure-based
Wide Temperature Range Testing with ROTEM Coagulation Analyses.
Mild induced hypothermia is used for neuroprotection in patients successfully resuscitated after cardiac arrest. Temperature-dependent effects on rotational thromboelastometry (ROTEM(®)) assays with EXTEM(®), FIBTEM(®), or APTEM(®) in cardiac arrest patients have not previously been studied. Ten patients with out-of-hospital cardiac arrest who underwent induced hypothermia were studied during stab
Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics.
Wilms tumor (WT) is a pediatric tumor of the kidney, the treatment of which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment of relevant orthotopic WT xenografts is important to better understand mechanisms of WT growth and for preclinical drug testing.
Water recovery and recycle in the PVC production: A novel approach using membrane technology
The production of 1 ton of PVC requires 2.0 - 2.5 m3 of demineralised water. Some of the water is lost in the process, e.g. as vapor during the drying of the PVC or as sealing water, while approx. 80% of the water could potentially be recycled. In today’s installations only about 20 – 25% of the water recovered by the PVC decanter is used for flushing of the facilities, while 75 – 80% is discharge
Miljonprogrammet – utskällt och missförstått
I höst är det 50 år sedan Skärholmens centrum invigdes, ett av de områden som tydligast kommit att symbolisera det svenska miljonprogrammet. Men rekordårens bostadspolitik styrdes inte av en kallhamrad socialdemokratisk människosyn.
Membrane processes for the bioethanol industry: New applications and challenges
„White biotechnology“- the third and latest wave of biotechnology - is aiming to replace the well-established C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. One of the key concepts related to “white biotechnology” are so
Protein-Protein Interactions in Human Aquaporin Regulation
Every living organism is made up of cells, the smallest structural and functional unit of life. These organisms can further be classified on the basis of cell number as single-cell or multi-cell organism. Over time these primitive organisms have evolved leading to the formation of more complex machinery in higher organism. While it is tough and tedious to calculate the exact number of cells in theWater is an essential compoment of every living orgamism and forms a major part of the human body. Regulated water transport is crucial for proper cell functioning and body homeostasis. Cell, the smallest structural and functional unit of life, uses specialized water conducting pores made up of proteins to transport water across the plasma membrane by facilitated diffusion.The discovery of one of
Membrane processes in biorefineries: From feedstock preparation to downstream processing
1. IntroductionThe third and latest wave of biotechnology is the so called „white biotechnology“ aiming to replace the C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. In the past, fermentation processes had to partly comp
Membrane processes in biorefineries: Opportunities and challenges to integrate membrane processes
Biorefineries are integrated biotech facilities aiming on full utilization of feedstock for the simultaneous production of e.g. food, biofuels and biochemicals. This presentation will provide an overview supported by case and application studies on the integration of membrane processes into biorefineries. Starting with the pre-treatment of the raw material e.g. wood biomass or starch, micro- (MF)
