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BACKGROUND: Macrophage foam cell formation is a prominent feature of human atherosclerotic plaques, usually considered to be correlated to uptake of and inflammatory response to oxidized low density lipoproteins (OxLDL). However, there are alternative pathways for formation of macrophage foam cells and the effect of such lipid loading on macrophage function remains to be fully characterized. In th
Abstract is not available
Objective: To evaluate the cumulative risk of having a prostate cancer diagnosis in a repeated screening situation in relation to the free-to-total prostate specific antigen ratio (F/T-PSA). Patients and Methods: The present study includes 1385 men (aged 50-70 years) who underwent prostate biopsy for the first time in the screening program that started in 1995. In case of a benign finding, the men
A 4 pi silicon bail for detection and identification of light charged particles in large multidetector gamma-arrays as EUROBALL is presented. The design is based on a N = 42 ball with 12 pentagons and 30 hexagons as used in the GASP array. The absorptive material for gamma-rays is minimized to the detector thickness of 300 or 500 mu m and a 0.63 mm ceramic backing. The geometrical coverage is desi
OBJECTIVE: to analyse the impact of stent-graft (SG) design and operator skill on the outcome of endovascular AAA repair. DESIGN: prospective non-randomised open. MATERIAL: a total of 158 patients (mean age 71) underwent SG repair. Patients were treated with five different types of SG: first (n =58) and second ( n =17) generation Ivancev-Malmo monoiliac SG (IM I and IM II respectively) combined wi
Abstract. AIMS: Can a cut-off blood pressure level for major complications be identified? METHODS: A 10 years observation study in 385 type 2 diabetic patients. RESULTS: 158 patients were affected with myocardial infarction, stroke, renal failure or death, which occurred in 68, 55, 19 and 109 patients, respectively. No patient with a blood pressure below 140 mmHg and/or a diastolic blood pressure
The main objectives of this study were to outline the inter-and intraindividual and overall pharmacokinetic variability of S-citalopram, S-desmethylcitalopram, and S-didesmethylcitalopram in serum by means of therapeutic drug monitoring; and to investigate potential correlations between the serum concentration and simultaneously collected clinical data. The study was conducted on outpatients in Sw
Bulgarian apico-alveolar stops and Swedish dorsovelar stops are palatalized when adjacent to front vowels. An X-ray motion film study of these assimilations (part of an ongoing investigation of the temporal organisation of coarticulation and assimilation) is presented. Two issues are examined, extrinsic vs intrinsic production of assimilation and feature spreading vs. coproduction. The articulator
This paper treats propagation of transient waves in nonstationary media, which has many applications in, for example, electromagnetics and acoustics. The underlying hyperbolic equation is a general, homogeneous, linear, first-order 2×2 system of equations. The coefficients in this system depend on one spatial coordinate and time. Furthermore, memory effects are modeled by integral kernels, which,
Background: A polymorphism in the activating component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex, neutrophil cytosolic factor 1 (NCFI), has previously been identified as a regulator of arthritis severity in mice and rats. This discovery resulted in a search for NADPH oxidase- activating substances as a potential new approach to treat autoimmune disorders such as rh
This dissertation is based on three questions:What is orality, how has orality developed during the last 200 years in Swedish non-fiction, and what is the cause of this development? Orality is treated here as the linguistic consequence of a certain communicative function. The basis is the different conditions of speech and writing and the different styles and features that are determined by these
Popular Abstract in Swedish Artros i knäleden är en av de tio vanligaste orsakerna till smärta och funktionshinder hos vuxna. Ett av problemen med artros är att det är svårt att diagnosticera vid ett tidigt stadium. Det kan synas som förändringar på röntgen, men ofta inte förrän flera år efter att det utvecklats. Mina studier visar att det finns ett samband mellan muskelfunktion i benen och riskenThe overall purpose of this thesis was to explore the impact of exercise and functional performance on development and treatment of knee osteoarthritis in the middle aged. In this thesis, I have studied a population based cohort of middle-aged subjects (35-54 years, 42 % women) with chronic knee pain at baseline, to evaluate the longitudinal effect of muscle weakness on knee osteoarthritis develo
The present study concerns 73 patients with known unilateral breast carcinoma. Thirty of the patients had a primary invasive carcinoma removed and at a later operation contralateral subcutaneous mastectomy with implantation of a prosthesis. This was performed with or without ipsilateral breast reconstruction. Forty-three of the cases had an in situ carcinoma found by local excision, whereafter bil
The paper presents a study of the influence of the conditions applied during differential scanning calorimetry (DSC) Measurements (concentration and heating rate) oil the possible detection of the differences between gelatinization occuring in both non-irradiated and irradiated potato starch with a dose of 20kGy. Differences in gelatinization of irradiated and non-irradiated potato starch during D
Background: An increasing number of industrial robots are being programmed using CAR (Computer Aided Robotics). Sensor guidance offers a means of coping with frequent product changes in manufacturing systems. However, sensors increase the uncertainty and to preserve system robustness, a tool is needed that makes it possible to understand a sensor guided robot system before and during its actual op
The c(5 root 2 x root 2)R45 degrees-Pb/Cu(100) surface phase is investigated by means of angle resolved ultraviolet photoemission and low energy electron diffraction in the temperature range between 300 and 550 K. We identify and characterize a temperature-induced surface phase transition at 440 K from the room temperature e(5 root 2 x root 2) R45 degrees phase to a (root 2 x root 2)R45 degrees st
