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Die in-vitro Perfusion der menschlichen Plazenta mit Eryhtrozyten und Xanthine Oxidase als in vitro Simulation von Praeeklampsie.

BACKGROUND AND PURPOSE: Preeclampsia is a major obstetric problem of unknown etiology. The fact that removal of the placenta is the only cure for preeclampsia, has led to the well-established hypothesis, that the placenta is central in the etiology. Gene profiling and proteomics studies have suggested oxidative stress caused by reperfusion and free oxygen radicals as a potential pathophysiological

Preservation conditions and the use of sediment pigments as a tool for recent ecological reconstruction in four Northern European estuaries

Down-core sediment pigment concentrations from four Northern European estuaries were measured using high-performance liquid chromatography (HPLC) to investigate phytoplankton community structure and preservation conditions over the last ca. 100 years where all sites have experienced different levels of eutrophication. Phytoplankton pigments have been shown to be useful biomarkers for phytoplankton

Situating language register across the ages, languages, modalities, and cultural aspects : Evidence from complementary methods

In the present review paper by members of the collaborative research center "Register: Language Users' Knowledge of Situational-Functional Variation" (CRC 1412), we assess the pervasiveness of register phenomena across different time periods, languages, modalities, and cultures. We define "register" as recurring variation in language use depending on the function of language and on the social situ

AP-XPS Study of Ethanol Adsorption on Rutile TiO2(110)

The photoactivity of rutile TiO2(110) renders its surfaces of particular interest for the study of surface reactions. In particular, rutile TiO2(110) surfaces are active for hydrogen production, both via the water splitting process and via ethanol degradation under ultraviolet illumination. The selective photocatalytic dehydrogenation of rutile TiO2(110) is not fully understood yet, and an importa

Strongly reduced optical absorption efficiency of soot with addition of potassium chloride in sooting premixed flames

Optical properties of soot have been investigated with and without potassium chloride (KCl) salt added to the soot formation process in a premixed ethylene/air flame. A strong decrease in optical absorption efficiency of the soot was observed with increasing amounts of KCl added to the fuel based on the method of fluence curve analysis using laser-induced incandescence (LII). To understand the rea

An evaluation of the critical conditions for the initiation of stress corrosion cracking in unidirectional E-glass/polymer composites

The purpose of this work is to establish the critical surface conditions leading to the initiation of stress-corrosion cracks on the assupplied surfaces of three unidirectional E-glass/polymer composites with modified polyester, epoxy and vinyl ester resins subjected to a nitric acid solution without mechanical loads. The composite materials considered in this study are commonly used in composite

Claims in the clinic: tensions in healthcare communication about perceived side effects of the copper IUD

A large share of health-related information is today sought and communicated via the internet, including in social media. Questions have been raised about how this may affect health perceptions and behaviors, not least by enabling the communication of claims that contradict information from established medical authorities. As an example, knowledge claims about systemic side effects of the contrace

Ideas with Histories : Traditional Knowledge Evolves

Abstract in FrenchDepuis longtemps, les anthropologues sont fascinés par les adaptations similaires et les différences intrigantes des cultures circumpolaires. Ces tendances ont été cartographiées, étudiées et interprétées sous différents angles, souvent à des niveaux sociaux ou spatiotemporels différents. Même si ces études ont produit d’importantes quantités de données, celles-ci ne couvrent pasAnthropologists have long been fascinated by the strikingly similar adaptations of circumpolar cultures as well as their puzzling differences. These patterns of diversity have been mapped, studied, and interpreted from many perspectives and often at different social and spatiotemporal scales. While this work has generated vast archives of legacy data, it has also left behind a fragmented understan

Interface reduction technique for Enhanced Craig-Bampton method

Substructure coupling and model order reduction using Component Mode Synthesis (CMS) have, over recent years, gained considerable attention in the vibroacoustic analysis of complex structures. In the CMS methodology, the interior dynamics of each subcomponent in a substructured system are represented by a truncated set of normal modes within the lower frequency range, while all physical degrees of

Sequentially N-Doped Acceptor Primer Layer Facilitates Electron Collection of Inverted Non-Fullerene Organic Solar Cells

In most non-fullerene organic solar cells comprising bulk-heterojunction active layers, the inter-domain connectivity of small-molecule acceptors is generally inferior to those of polymeric donors due to their intrinsic short-range ordering. This issue is even exacerbated by the physiochemical mismatch between acceptor-phases and metal-oxide electron transport layers in most inverted n-i-p devices

Men's Attitudes Towards Participation in Organised Prostate Cancer Testing: An Abductive Thematic Analysis

Background and objectiveOrganised prostate cancer (PCa) testing (OPT) was introduced in Sweden to gain knowledge in preparation for a potential national PCa screening programme. This study aims to explore men’s opinions regarding the OPT invitation letters and the attitudes influencing their decision to participate in or decline OPT.MethodsWe conducted semi-structured telephone interviews with 30

Mircostructure and rheological properties of concentrated tomato suspensions during processing

Food processing comprises operations such as dilution (changing the concentration), homogenisation (changing the particle size), and subsequent pumping (shearing), among others. It is thus of great interest to gain a better understanding of the mechanisms governing the creation and disruption of structures during these engineering operations, and the way in which they are related to the textural a

Audience Research and Multimodality: What Eye Tracking Reveals about Newspaper Reading

On closer inspection, the so-called iconic turn in recent media history is a multimodal turn. Media communication has not only been enriched by pictures but has turned from a text-medium into a multi-medium, i.e. into a complex system of different modes like design, colours, pictures, graphics, and typography. Along with the multimodal turn, the linear structure of media communication has become n

Highest Vaccine Uptake after School-Based Delivery - A County-Level Evaluation of the Implementation Strategies for HPV Catch-Up Vaccination in Sweden

BACKGROUND: The Swedish school-based vaccination programme offers HPV vaccine to girls born ≥1999 in 5-6th grade. In 2012, all counties introduced free-of-charge catch-up vaccination campaigns targeting girls born 1993-1998. Varying vaccine uptake in the catch-up group by December 2012 suggested that some implementation strategies were more successful than others. In order to inform future vaccina

Expression of recombinant soluble and membrane-bound catechol O-methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain

The rat and human recombinant soluble and membrane-bound catechol O-methyltransferase (S- and MB-COMT, respectively) were expressed using mammalian and baculovirus vectors. Low levels of rat and human S-COMT polypeptides were detected by immunoprecipitation in K-562 cell lines transfected with the S-COMT vectors. From K-562 cells transfected with the rat MB-COMT construct, both S- and MB-COMT reco

Development of Second and Third Generation Bioelectronics

The field of research dealing with the integration of biomolecules with electronic elements to form functional devices is called ‘‘bioelectronics’’. Bioelectronics based on mediated electron transfer (MET) between the biological element and the electrodes are designated as “second generation” while the one based on direct electron transfer (DET) is specified as “third generation”. Implanted bioele

Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii

Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. Dysfunctional telomeres are implicated in many complex cellul

Shrub expansion in tundra ecosystems: dynamics, impacts and research priorities

Recent research using repeat photography, long-term ecological monitoring and dendrochronology has documented shrub expansion in arctic, high-latitude and alpine tundra ecosystems. Here, we (1) synthesize these findings, (2) present a conceptual framework that identifies mechanisms and constraints on shrub increase, (3) explore causes, feedbacks and implications of the increased shrub cover in tun

Seasonal variation of atmospheric particle number concentrations, new particle formation and atmospheric oxidation capacity at the high Arctic site Villum Research Station, Station Nord

This work presents an analysis of the physical properties of sub-micrometer aerosol particles measured at the high Arctic site Villum Research Station, Station Nord (VRS), northeast Greenland, between July 2010 and February 2013. The study focuses on particle number concentrations, particle number size distributions and the occurrence of new particle formation (NPF) events and their seasonality in