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Atrial time and voltage dispersion are both needed to predict new-onset atrial fibrillation in ischemic stroke patients

Background: Atrial fibrillation (AF) is a known risk factor for ischemic stroke. Electrocardiographic predictors of AF in population studies such as the Framingham Heart Study, as well as in hypertensive patients have demonstrated a predictive value of the P-wave duration for development of AF. QRS vector magnitude has had a predictive value in ventricular arrhythmia development. We aimed to asses

Energy-Efficient Application-Specific Instruction-Set Processor for Feature Extraction in Smart Vision Systems

Smart vision sensor systems enable many computer vision applications such as autonomous drones and wearable devices. These battery-powered gadgets have very stringent power consumption requirements. Close-to-sensor feature extraction compressing the full image into descriptive keypoints, is crucial as it allows for several design optimizations. First, the amount of necessary on-chip memory can be

Cardiomyopathy among first- and second-generation immigrants in Sweden : a nationwide total population study

Purpose: We aimed to analyze the risk of cardiomyopathies (CMPs) among first-generation and second-generation immigrants. Methods: All individuals aged 18 years of age and older, n = 6,123,661 in the first-generation study, and n = 4,587,764 in the second-generation study were analyzed. CMP was defined as at least one registered diagnosis in the National Patient Register between January 1, 1998 an

Changes in Athletic Performance in Children Attending a Secondary School with a Physical Activity Profile

The longitudinal and multidisciplinary research project Malmö Youth Sport Study measured the sports results achieved by two cohorts of pupils using a variable named ACHIEVE, dividing the pupils into three categories (an elite group competing at the national or international level, a group competing at the district level, and a third group either not competing at all or below district level). This

A review on the applications of machine learning for runoff modeling

The growing menace of global warming and restrictions on access to water in each region is a huge threat to global hydrological sustainability. Hence, the perspective at which hydrological studies are currently being carried out across the world to quantify and understand the water cycle modeling requires a further boost. In the past few decades, the theoretical understanding of machine learning (

GDNF Therapy : Can We Make It Work?

In two recent postmortem studies, Jeffrey Kordower and colleagues report new findings that open up for an interesting discussion on the status of GDNF/NRTN signaling in patients with Parkinson's disease (PD), adding an interesting perspective on the, admittedly very limited, signs of restorative effects previously seen in GDNF/NRTN-treated patients. Their new findings show that the level of the GD

Anterior uveitis in patients with spondyloarthritis treated with secukinumab or tumour necrosis factor inhibitors in routine care : Does the choice of biological therapy matter?

Background: The effect of interleukin 17-inhibitors on anterior uveitis (AU) in spondyloarthritis (SpA) is poorly understood. This study aimed to compare the risk of AU during treatment with secukinumab versus tumour necrosis factor inhibitors (TNFi). Methods: Patients with SpA starting secukinumab or a TNFi 2015 through 2018 were identified in the Swedish Rheumatology Quality Register. Occurrence

Structural insights into AQP2 targeting to multivesicular bodies

Vasopressin-dependent trafficking of AQP2 in the renal collecting duct is crucial for the regulation of water homeostasis. This process involves the targeting of AQP2 to the apical membrane during dehydration as well as its removal when hydration levels have been restored. The latter involves AQP2 endocytosis and sorting into multivesicular bodies (MVB), from where it may be recycled, degraded in

A novel mutation (N233K) in the transactivating domain and the N756S mutation in the ligand binding domain of the androgen receptor gene are associated with male infertility

OBJECTIVE: Resistance to androgens has been suggested as a possible cause of male infertility. This hypothesis is based mainly on binding studies in genital skin fibroblasts but the molecular evidence is sparse. DESIGN: Molecular studies of the androgen receptor gene were performed in 10 azoo- or oligozoospermic men, precenting with clinical signs of low androgen activity - poor virilization and h

Associations of Pregnancy Dietary Quality and Diversity with Childhood Celiac Disease

Background: High gluten and low dietary fiber in pregnancy intake is associated with an increased risk of celiac disease (CeD) in the child. Early life higher dietary quality is suggested to reduce the subsequent risk of CeD. Objectives: The aim was to investigate associations of pregnancy dietary quality and diversity with child risk of CeD. Methods: In The Norwegian Mother, Father and Child Coho

Screening for comorbid autoimmune disease should be considered in children with ANA positive juvenile idiopathic arthritis – results from the south-Swedish juvenile idiopathic arthritis cohort

Background: There is no consensus or clinical guidelines for screening routines of autoimmune disease in individuals with juvenile idiopathic arthritis (JIA), since results are conflicting whether the risk for such conditions is increased or not among individuals with JIA. The aim of this study was to investigate if the frequency of comorbid autoimmune conditions is increased after JIA diagnosis i

Co-creating urban development : local Swedish projects guided by Universal design

This chapter summarizes my doctoral thesis about Universal Design (UD) in Sweden, contributing knowledge about the understanding, implementation, and co-creation of UD. The implementation of the UN Convention on the Rights of Persons with Disabilities in Sweden made UD a guiding principle, necessitating research about the practical side of UD. Using qualitative research methods, interviews and gro

EUROFEL : Europe tackles key issues of free electron lasers

During the last few years Europe has made enormous progress towards free electron laser (FEL)-based research infrastructures. The FLASH facility [1] at DESY in Hamburg, Germany, has been in user operation since the summer of 2005; FERMI@Elettra [2] in Trieste, Italy, is under construction; the European XFEL [3] in Hamburg will start construction in summer 2008; and several other FEL projects are b

The Integrated Carbon Observation System (ICOS) : Standardised observations for science and societies

To understand, predict and mitigate climate change, it is crucial to have long-term and standardised measurements of greenhouse gas concentrations in the atmosphere and their fluxes between atmosphere, land and oceans. The Integrated Carbon Observation System, is a distributed European Research Infrastructure which provides high-precision and highly standardised observations from more than 170 sta

Accountabilities, invisibilities and silences in a Danish slave trading company on the Gold Coast in the early 18th century

Using eighteenth-century archival material from a Danish trading fort in West Africa, we explore how accounting and accountability systems were complicit with the crafting and narration of racialized slave trading during mercantile colonialism. By examining the role of accounting not at the slave trade's endpoint, e.g., plantations in the Americas, but at its points of extraction, we reveal the ro

Cardiac Enlargement in a Medicolegal Autopsy Setting

A key element for diagnosing cardiac enlargement in an autopsy setting is relevant heart weight references. However, most available references are to a large extent not representative of a medicolegal autopsy population, implying that reference weights are likely lower than those in the relevant population.To establish more applicable heart weight references in a medicolegal autopsy population, we

ISLAND, A SITE SPECIFIC AND HUMAN SPECIFIC PERFORMANCE ABOUT WHAT IT MEANS TO BELONG

ISLAND, A SITE SPECIFIC AND HUMAN SPECIFIC PERFORMANCE ABOUT WHAT IT MEANS TO BELONG (VIDEO ESSAY: 22 MINUTES)ABSTRACTThe video essay disseminates the work Eyja (island), a site specific, participatory performance from autumn 2020 performed in Hrísey an Island off the north coast of Iceland. Island is a part of an artistic research project: How little is Enough? Sustainable Methods of Performance

‘Newton’ fast shutter system for neutron scattering instruments at the ESS and ISIS neutron sources

Interfacial processes are involved in many areas of chemistry, physics and biochemistry, but following the structural changes of surfaces and thin films at relevant timescales remains challenging. Time-of flight neutron reflectometry can determine changes in surface composition and film thickness, but the speed of these measurements is typically limited by the neutron flux over the range of wavele

Constructing clickable criminal trials: : Framing trials and legal professionals in digital news reports

Journalistic live blogging entails the conundrum of capturing emotions in a context where they should be absent in order to snap up the sensational in the subtle drama of the courtroom and present it in a way that attracts readers, thus making it clickable.Applying an inductive frame analysis of live blogs and drawing on criteria of newsworthiness and an emotion sociological framework, this articl

A Study Program for Doctoral Supervisors – a Vehicle for Development

A study program for doctoral supervisors is currently being implemented at two higher education institutions: One large and traditional research university and one university college. The overall aim of the program is to improve supervision as well as local practices for doctoral education and doctoral research in departments and research groups but also at the institutional level. In planning the