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Therapy Effects in Cerebral Folate Transport Deficiency with Hypomyelination Monitored by Multimodal Quantitative MR-Imaging

Myelin-sensitive quantitative (q) MRI techniques including MT (3D FLASH) and DTI (single-shot STEAM) are of growing importance to study white matter (WM) disorders in childhood. Cerebral folate transport deficiency is an inherited, treatable WM disorder with hypomyelination, developmental regression, movement disturbances, and epilepsy. One patient with this diagnosis and severe phenotype was trea

On Author, Copyright and Originality: does the unified EU originality standard correspond to the digital reality in Wikipedia?

This article is contributing to the future of copyright law debate by exploring the recently harmonised originality standard in the EU copyright law and its suitability to a creative sharing community of Wikipedia. It shows that the “free creative choices” and “author’s personal” touch criteria established by the CJEU might be unsuitable not only because of practical concerns, but also because the

Effects of Acute Exercise on Circulating Soluble Form of the Urokinase Receptor in Patients With Major Depressive Disorder

Inflammation has been proposed to play a role in the generation of depressive symptoms. Previously, we demonstrated that patients with major depressive disorder (MDD) have increased plasma levels of the soluble form of the urokinase receptor (suPAR), a marker for low-grade inflammation. The aim of this study was to test the hypothesis that acute exercise would induce inflammatory response characte

TruSDN: Bootstrapping Trust in Cloud Network Infrastructure

Software-Defined Networking (SDN) is a novel architectural model for cloud network infrastructure, improving resource utilization, scalability and administration. SDN deployments increasingly rely on virtual switches executing on commodity operating systems with large code bases, which are prime targets for adversaries attacking the network infrastructure. We describe and implement TruSDN , a fram

Assessing cereal grain quality with a fully automated instrument using artificial neural network processing of digitized color video images

A fully integrated instrument for cereal grain quality assessment is presented. Color video images of grains fed onto a belt are digitized. These images are then segmented into kernel entities, which are subject to the analysis. The number of degrees of freedom for each such object is decreased to a suitable level for Artificial Neural Network (ANN) processing. Feed- forward ANN's with one hidden

Numerical analysis on thermal performance of cooling plates with wavy channels in PEM fuel cells

Purpose: The purpose of this paper is to investigate the thermal performance of the cooling plates with conventional straight channel and wavy channel designs. Design/methodology/approach: A three-dimensional model involving coupled fluid flow and heat transfer processes is developed to study the thermal performance of the cooling plates. The effects of wavelength and amplitude on the cooling perf

GARD : Genomic allergen rapid detection

Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and

Post-cardiac arrest care. Targeted temperature management and coronary care.

AbstractOut-of-hospital cardiac arrest is a devastating manifestation of coronary artery disease. For patients who are initially resuscitated and are admitted to an intensive care unit, mortality is high. Roughly half of all patients die, primarily due to neurological injury. In recent years, some improvement in outcomes has been seen, perhaps in some part due to interventions performed in hospita

Power Market Structure and Renewable Energy Deployment Experiences From the MENA Region

In almost all countries in the Middle East and North Africa (MENA) region, power sectors are characterized by a high degree of vertical integration and state control. However, several countries have undertaken reforms in order to open up the power market for private sector involvement particularly in relation to renewable energy (RE) sourced electricity generation. The majority of the MENA countri

Landscape Theology : Exploring the Outfields of the Telemarkian Dream Song

The article explores the Norwegian ‘national ballad’ Draumkvæde (the Dream Song) in Maren Ramskeid’s version. This work has traditionally been interpreted as a folklore adaptation of medieval visionary literature such as the Vision of Tundale, related to Dante Alighieri’s Divine Comedy. The ballad, however, lacks demons and devils and infernal torture – it is even almost completely devoid of humanThe article explores the Norwegian ‘national ballad’ Draumkvæde (the Dream Song) in Maren Ramskeid’s version. This work has traditionally been interpreted as a folklore adaptation of medieval visionary literature such as the Vision of Tundale, related to Dante Alighieri’s Divine Comedy. The ballad, however, lacks demons and devils and infernal torture – it is even almost completely devoid of human

The predictive power of the National Early Warning Score (NEWS) 2, as compared to NEWS, among patients assessed by a Rapid response team : A prospective multi-centre trial

Aim: Early identification of patients at risk of serious adverse events (SAEs) is of vital importance, yet it remains a challenging task. We investigated the predictive power of National Early Warning Score (NEWS) 2, as compared to NEWS, among patients assessed by a Rapid response team (RRT).Methods: Prospective, observational cohort study on 898 consecutive patients assessed by the RRTs in 26 Swe

(O)trygghet i Göteborg? : Från kust till inland

Vid tiden för Göteborgs 400-årsjubileum var ordet trygghet på många av göteborgarnas läppar. Göteborgs Stad hade sedan några år inlett ett tydligt fokus på att försöka öka invånarnas trygghet genom projekt som ”Trygg i Göteborg” och genom polisiära insatser för att minska den organiserade brottsligheten. Med tanke på sådana insatser tedde det sig kanske inte underligt att hela 15 procent av de sva