Pan-cancer validation of a lung-adenocarcinoma-derived gene-expression-based prognostic predictor
Gene expression profiling can be used to classify lung adenocarcinoma tumors into molecular subtypes that also correlate with patient prognosis. Knowing these subtypes can help clinicians save lives by directing surgery and adjuvant therapy efforts, provided adequate clinical validation. It is less well-known how generalizable prognostic gene signatures derived in one malignancy are in a pan-cance
