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The intra- and inter-day repeatability of corneal densitometry measurements in subjects with keratoconus and in healthy controls

The healthy cornea is transparent, however, disease can affect its structure, rendering it more or less opaque. The ability to assess the clarity of the cornea objectively could thus be of considerable interest for keratoconus patients. It has previously been suggested that densitometry can be used to diagnose early keratoconus, and that the values of densitometry variables increase with increasin

Novel and unusual genes for nitrogen and metal cycling in Planctomycetota- and KSB1-affiliated metagenome-assembled genomes reconstructed from a marine subsea tunnel

The Oslofjord subsea road tunnel is a unique environment in which the typically anoxic marine deep subsurface is exposed to oxygen. Concrete biodeterioration and steel corrosion in the tunnel have been linked to the growth of iron- and manganese-oxidizing biofilms in areas of saline water seepage. Surprisingly, previous 16S rRNA gene surveys of biofilm samples revealed microbial communities domina

gm/Id Analysis of vertical nanowire III–V TFETs

Experimental data on analog performance of gate-all-around III-V vertical Tunnel Field-Effect Transistors (TFETs) and circuits are presented. The individual device shows a minimal subthreshold swing of 44 mV/dec and transconductance efficiency of 50 V−1 for current range of 9 nA/μm to 100 nA/μm and at a drain voltage of 100 mV. This TFET demonstrates translinearity between transconductance and dra

Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy : An Integrative Epigenome Wide Association Study

Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430

Luminescence and radiocarbon dates from alluvial sediments, Podhale, Central Europe — A methods comparison

Optically stimulated luminescence (OSL) and radiocarbon (14C) techniques were employed to investigate the absolute ages of alluvial sediments in Podhale in the West Carpathians, southern Poland. This is an approach to (i) testing the credibility of the above dating methods by their reciprocal age control and (ii) further implications to regional geochronology and to dating campaigns of alluvial se

Observer-Based Plasma Glucose Prediction in Type I Diabetes

Recent years’ progress in the development of Continuous Glucose Monitors (CGM) has made rich well-sampled glucose data readily available. Reliable, frequent measurements are of outmost importance for the emerging closed-loop control of diabetic plasma glucose. However, these sensors do not measure the variable of primary interest - plasma glucose, but a delayed signal - the interstitial glucose. T

First radioactive ions charge bred in REXEBIS at the REX-ISOLDE accelerator

REXEBIS is the charge breeder of the REX-ISOLDE postaccelerator. Radioactive 1+ ions produced at ISOLDE are accumulated, phase-space cooled and bunched in REXTRAP, and thereafter injected into the EBIS with an energy of up to 60 keV. The REXEBIS produced the first charge bred ions in August 2001 and has been running nearly non-stop from September to December 2001. It has delivered stable 39K10+ an

A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis

Genetic factors influence susceptibility to multiple sclerosis but the responsible genes remain largely undefined, association with MHC class II alleles being the only established genetic feature of the disease. The Nordic countries have a high prevalence of multiple sclerosis, and to further explore the genetic background of the disease, we have carried out a genome-wide screen for linkage in 136

Rapid decline of persistent organochlorine pollutants in serum among young Swedish males

To investigate a possible time trend in serum concentrations of persistent organochlorine pollutants (POPs), representative samples of the young (median age 18 years) Swedish male population were investigated in the years 2000 and 2004. Due to their low age, these men were assumed not to have reached steady state of body burdens of POPs, why their serum concentrations were considered to represent

Amperometric monitoring of redox activity in intact, permeabilised and lyophilised cells of the yeast Hansenula polymorpha

An effect of permeabilisation and lyophilisation of the yeast cells Hansenula polymorpha on their electrochemical behaviour in the presence of mediators, substrates (formaldehyde, glucose, methanol, ethanol), and cofactors (NAD(+), NADP(+), NADH, NADPH, glutathione) has been studied. Two amperometric techniques differing in the cell immobilisation methods were applied. The cells of a wild strain (

Structure and Function of a Novel Type of ATP-dependent Clp Protease

The Clp protease is conserved among eubacteria and most eukaryotes, and uses ATP to drive protein substrate unfolding and translocation into a chamber of sequestered proteolytic active sites. The main constitutive Clp protease in photosynthetic organisms has evolved into a functionally essential and structurally intricate enzyme. The model Clp protease from the cyanobacterium Synechococcus consist

Intrapartum fetal ECG and diabetes

Aim. The objective of this study was to determine the prevalence and types of ST-segment changes of the fetal electrocardiogram (FECG) during labour in term fetuses born to mothers with diabetes mellitus (DM) or gestational diabetes. Methods. This was a retrospective case-control study involving populations from two multi centre trials: the Swedish Randomized Control Trial and the European Union S

The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.

Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia. Rats with unilateral 6-hydroxydopamine lesions were primed to exhibit l-DOPA-induced dyskinesia. They were then intrastriatally grafted with different quantities of embryonic ventral me

High density lipoprotein concentrations after cessation of smoking: the importance of alterations in diet

Cessation of smoking is followed by a rapid rise in plasma HDL concentrations. An earlier study has demonstrated a significant relationship between the increase in HDL concentrations and spontaneous changes in food intake, specifically an increased fat intake. In this investigation we have dissociated the effects of cessation of smoking as such from those of dietary alterations by monitoring plasm

Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women

The relationships between abdominal and pelvic fat compartments and glucose and lipid metabolism were investigated in early postmenopausal women. Fifty-five healthy, postmenopausal women aged 52-53 yr participated in the study. Fat distribution (intra-abdominal and sc abdominal fat, and intrapelvic and sc pelvic fat) was estimated by computed tomography. Insulin sensitivity was assessed by euglyce

Gas exchange function one month after transplantation of lungs topically cooled for 2 hours in the non-heart-beating cadaver after failed resuscitation

BACKGROUND: If lungs from subjects dying of heart attacks could be used for transplantation, the lung donor shortage could be radically reduced. The aim of this study was to investigate, in an experimental survival model, the results of lung transplantation using lungs from non-heart-beating donors. METHODS: The left lung, topically cooled to 25 degrees C for 2 hours in situ after 5 minutes of cir

Lunds-universitets-magasin-8-2012

Juristuppryckning gav toppbetyg Lätt att göra upphovsfel Isbjörnen kommer närmare Lunds universitets magasin | nr 8 | 2012 Klippan ett administratörsLiv i ständig förändring 2 LUM nr 8 | 2012 LUM nr 8 | 2012 3 Allt fältarbete på Svalbard måste följa säkerhetsregel nummer 1 – forskarna ska ha laddade gevär och ständigt speja efter isbjörnar. I den karga miljön på Svalbard har Lunds universitet bedr

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-8-2012.pdf - 2026-05-24