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Course literature Autumn 2014 FMPM03 Film and Media Producing: Entrepreneurship 15 ECTS Literature Barringer B. R. & Ireland, R.D. (2012) Entrepreneurship: Successfully launching new ventures , New Jersey: Pearson. (BI) Alexander Osterwalder ,  Yves Pigneur ,  Tim Clark (2010) Business Model Generation: A Handbook for Visionaries, Game Changers, and Challengers. John Wiley Sons   Collection of Art

https://www.sol.lu.se/media/utbildning/dokument/kurser/FMPM03/20142/Reading_List.docx - 2025-12-02

A naturally occurring allele of BRCA1 coding for a temperature-sensitive mutant protein

Recent evidence suggests that the breast and ovarian cancer susceptibility gene product BRCA1 is involved in at least two fundamental cellular processes: transcriptional regulation and DNA repair. However, the mechanism of action of BRCA1 in either of these processes is still unknown. Here, we report the characterization of a disease-predisposing allele of BRCA1, identified in a family with severa

Designing a generic user interface for distribution of open geodata : based on FME server technology

Mängden kostnadsfria kartor som finns tillgängliga genom nedladdningstjänster på internet kommer enligt trenden i samhället att öka. I och med det kommer även antalet nedladdningstjänster öka. Att fler kan tillgå kostnadsfria kartor kommer troligtvis leda till nya produkter och tjänster som kan öka effektiviteten för både privat och offentlig sektor. Nya tjänster kan även leda till bättre service,There are currently numerous web services that provide the user with the opportunity to download geodata. These services are often different regarding what type of data they provide and the way they distribute the data. Another aspect that differs between these services is if the download of geodata is free of charge (open) or subject to a fee. There is currently a trend in the society striving to

"Den som sa det han var det"- Om prövning av erkännanden ur ett rättssäkerhetsperspektiv

”Den som sa det han var det”. Ett klassiskt svenskt ordspråk företrädelsevis populärt bland barn att dra till med när argumentationen tagit slut i en hetsig diskussion. Men också en ypperlig titel på denna uppsats då den ger uttryck för en mycket vanlig uppfattning; den som erkänner brott måste också vara skyldig till detsamma. I Rättegångsbalken stadgas det att ett erkännande i brottmål endast tj"Den som sa det han var det." A classic Swedish saying, especially popular amongst children when found themselves run out of arguments in a heated discussion. But also an excellent title for this paper as it reflects a very common belief; the one who confesses a crime must also be guilty of the same. The Swedish law states that a confession in criminal cases only serve as evidence, which

Errors in medication history at hospital admission : Prevalence and predicting factors

Background: An accurate medication list at hospital admission is essential for the evaluation and further treatment of patients. The objective of this study was to describe the frequency, type and predictors of errors in medication history, and to evaluate the extent to which standard care corrects these errors.Methods: A descriptive study was carried out in two medical wards in a Swedish hospital

Malnutrition in geriatric patients : A neglected problem?

The nutrient intake in geriatric long-stay patients and the mortality risk associated with low energy intake were studied in 61 patients, 43 women and 18 men, with a mean age of 87 years, at a geriatric long-stay care hospital during a 6-month follow-up. Dietary intake was assessed with a 9-day dietary record. Energy expenditure was calculated assuming a physical activity level of 1.33 × basal met

The infected knee arthroplasty

Popular Abstract in Swedish Vid en knäprotesoperation ersätts ledytorna i knäet med en protes gjord av metall och plast. Den vanligaste orsaken till denna operation är artros(ledsvikt. Antalet knäprotesoperationer ökar stadigt och 2009 utfördes 12,700 förstagångsoperationer i Sverige. Resultaten är överlag goda men en allvarlig komplikation som drabbar mellan 1 och 2% av patienterna är bakterieinfThe Swedish Knee Arthroplasty Register (SKAR) was used to identify 478 cases that underwent a first-time revision with exchange or removal of the prosthesis due to infection during the years 1986–2000. 30% of the infections were diagnosed within 3 months from primary operation and two-thirds were diagnosed within 2 years. These cases frequently had a history of wound complication after the primar

Treatment with the sphingosine-1-phosphate analogue FTY 720 reduces loss of plasma volume during experimental sepsis in the rat.

BACKGROUND: Increased vascular leakage leading to hypovolaemia and tissue oedema is common in severe sepsis. Hypovolaemia together with oedema formation may contribute to hypoxia and result in multiorgan failure and death. To improve treatment during sepsis, a potential therapeutic target may be to reduce the vascular leakage. Substances affecting the endothelial barrier are interesting in this re

3,4-Diarylmaleimides-a novel class of kinase inhibitors-effectively induce apoptosis in FLT3-ITD-dependent cells

FLT3 kinase has become an attractive drug target in AML with up to 30% of cases harboring internal-tandem-duplication (ITD) mutations. For these, conferring a worse prognosis and decreased overall survival, several FLT3 tyrosine kinase inhibitors (TKIs) are currently being tested in clinical trials. However, when using these drugs as monotherapy, the problem of short duration of remissions and hig

Repeated Liver Resection for Colorectal Liver Metastases: A Comparison with Primary Liver Resections concerning Perioperative and Long-Term Outcome.

Introduction. 60% of patients operated for colorectal liver metastases (CRLM) will develop recurrent disease and some may be candidates for a repeated liver resection. The study aimed to evaluate differences in intraoperative blood loss and complications comparing the primary and the repeated liver resection for metastases of colorectal cancer (CRC), as well as to evaluate differences in long-time

Hospital readmissions among older people with intellectual disability in comparison with the general population

Background: Older people with intellectual disability have high multimorbidity and poor physical and mental health compared with the general population. Consequently, they have a greater need for health care. Hospital readmissions may be an indicator of the quality of health care. However, so far, only a few studies have investigated this outcome in populations of people with intellectual disabili

Roles of PDZ-dependent Interactions and N-glycosylation in G Protein-coupled Estrogen Receptor 1 (GPER1)/GPR30-mediated Stimulation of ERK1/2 Activity

G protein-coupled receptor 30 (GPR30) is a G protein-coupled receptor (GPCR) that is attracting considerable attention in breast cancer and cardiometabolic regulation. Following reports that GPR30 is required for some rapid estrogen responses, e.g. increased cAMP production and ERK1/2 activity, in estrogen receptor (ER)-negative cells, GPR30 was renamed G protein-coupled estrogen receptor 1 (GPER1

Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication after Cardiac Arrest

Importance: Neuroprognostication studies are potentially susceptible to a self-fulfilling prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining therapy. Objective: To compare the results of prognostic parameters after cardiac arrest (CA) with the histopathologically determined severity of hypoxic-ischemic encephalopathy (HIE) obtained from autopsy results. Design,

Towards gene-and gender-based risk estimates in Lynch syndrome; Age-specific incidences for 13 extra-colorectal cancer types

Background:In Lynch syndrome, inherited mismatch repair (MMR) defects predispose to colorectal cancer and to a wide spectrum of extra-colorectal tumours. Utilising a cohort study design, we aimed to determine the risk of extra-colorectal cancer and to identify yet unrecognised tumour types.Methods:Data from 1624 Lynch syndrome mutation carriers in the Danish hereditary non-polyposis colorectal can

Benchmarking subcellular localization and variant tolerance predictors on membrane proteins

Background: Membrane proteins constitute up to 30% of the human proteome. These proteins have special properties because the transmembrane segments are embedded into lipid bilayer while extramembranous parts are in different environments. Membrane proteins have several functions and are involved in numerous diseases. A large number of prediction methods have been introduced to predict protein subc

Special supervisory homes in Sweden : paper presented September 12:th at the 7:th EUSARF Congress 2002 in Trondheim : Revitalising Residential and Foster Care

Sweden is the only Scandinavian country that uses closed treatment institutions based on coercive measures within the child welfare system, on a large scale, for the education and treatment of young criminal offenders and drug users. In Sweden there are in 2002 some 30 “homes for specialized supervision” of varying sizes and degrees of specialization – all run by a national board of institutional

Validation of the Swedish Knee Arthroplasty Register: a postal survey regarding 30,376 knees operated on between 1975 and 1995

The Swedish Knee Arthroplasty Register is dependent on the participating clinics regarding accuracy of information. As the register is prospective, and since revision is used as the endpoint in survival analyses, it is important that all revisions of registered primary arthroplasties are reported. To validate the register, we sent a questionnaire to all living patients with 30,796 knees registered

Topics in Trajectory Generation for Robots

A fundamental problem in robotics is generating the motion for a task. How to translate a task to motion or a series of movements is a non-trivial problem. The complexity of the task, the structure of the robot, and the desired performance determine the sequence of movements, the path, and the course of motion as a function of time, namely the trajectory. As we discuss in this thesis, a trajectory

Extent of salmeterol-mediated reassertion of relaxation in guinea-pig trachea pretreated with aliphatic side chain structural analogues

1. Salmeterol is a potent, selective and long acting beta 2-adrenoceptor agonist. In vitro, salmeterol exerts 'reassertion' relaxation of airways smooth muscle. Reassertion relaxation refers to the capacity of salmeterol to cause repeated functional antagonism of induced contraction when airway smooth muscle is intermittently exposed to, then washed free from, beta-adrenoceptor antagonists such as

Preparation of a portable point-of-care in vitro diagnostic system, for quantification of canine C-reactive protein, based on a magnetic two-site immunoassay.

In this study, characterization of the binding kinetics and optimization of a magnetic permeability based point-of-care (POC) immunoassay system for quantification of canine C-reactive protein (cCRP) is described. The reagent is based on a two-site heterogeneous immunoassay system utilizing conjugated superparamagnetic nanoparticles (SPION) and silica particles, both particles carrying covalently