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Inference to the Best Explanation (IBE) and Archaeology: Old Tool, New Model.

The last decades have seen a renewed interest in the study of argumentation in archaeology, particularly in response to the overproduction of weak and unreliable interpretations and explanations. Concurrently, recent appeals for scientific transparency and efficiency in the management of archaeological information in digital form have stressed the necessity of explicitly showing the processes foll

Unlocking the health system barriers to maximise the uptake and utilisation of molecular diagnostics in low-income and middle-income country setting

Background Early access to diagnosis is crucial for effective management of any disease including tuberculosis (TB). We investigated the barriers and opportunities to maximise uptake and utilisation of molecular diagnostics in routine healthcare settings. Methods Using the implementation of WHO approved TB diagnostics, Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) and Line Probe Assay (LPA

Sodium-glucose co-transporter inhibitors and atrial fibrillation : A systematic review and meta-analysis of randomized controlled trials

BACKGROUND: Sodium-glucose co-transporter (SGLT) inhibitors reduce cardiovascular outcomes including mortality in several populations; however, their effect on atrial fibrillation/flutter (AF) remains unclear. Our objective was to determine whether SGLT inhibitors reduce AF and whether a history of AF modifies the effect of SGLT inhibitors on the composite of heart failure hospitalization or cardi

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Master’s Dissertation Structural Mechanics FREDRIK STEFFEN WIND-INDUCED VIBRATIONS IN HIGH-RISE BUILDINGS DEPARTMENT OF CONSTRUCTION SCIENCES STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--16/5211--SE (1-66) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisor: PETER PERSSON, PhD, Div. of Structural Mechanics, LTH. Examiner: Professor PER-ERIK AUSTRELL, Div. of Structural Mechanics, LTH. Copyright © 2016 Div

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5211.pdf - 2026-05-23

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Acc nr: M 6570:1-154 Landskap: Småland Upptecknat av: Carl Viking Härad: Uppvidinge Adress: Furåkra, Kråksmåla sn Socken: Älghult Berättat av: f d lantbrukaren Isak Jansson Uppteckningsår:1940 Född år 1822 i Älghult sn Uppteckningen berör mina egna upplevelser så långt jag med visshet minns t o m ovanskrivna uppteckningsår. --------------------------------------------------------------------------

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/M6570.pdf - 2026-05-23

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Matematikcentrum Matematik NF Sammanställning för MATA03 Matematik för naturvetare 1, vårterminen 2023 Kursansvarig: Anna-Maria Persson Övriga lärare: Malin Christersson, Frej Weiström-Dahlin, Henrik Ekström, Raul Hindov Antal studenter: 53 nyregistrerade studenter samt 4 studenter omregistrerade på MATA02, den tidi- gare versionen av kursen, har deltagit i kursen. 16 studenter har besvarat utvärd

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2023/MATA03VT23.pdf - 2026-05-23

Little Doubt That CBT Works for Pediatric OCD

We write with great concern in response to the recent systematic review and meta-analysis of cognitive-behavioral therapy (CBT) in pediatric obsessive-compulsive disorder (OCD) by Uhre et al.1 Although the authors’ results consistently support the clinical efficacy of CBT for pediatric OCD, we expect that, much like ourselves, readers will be confused by the discordant and inappropriate conclusion

Excess Morbidity Persists in Patients With Cushing's Disease During Long-term Remission : A Swedish Nationwide Study

CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver

The spatiotemporal distribution of human pathogens in ancient Eurasia

Infectious diseases have had devastating effects on human populations throughout history, but important questions about their origins and past dynamics remain1. To create an archaeogenetic-based spatiotemporal map of human pathogens, we screened shotgun-sequencing data from 1,313 ancient humans covering 37,000 years of Eurasian history. We demonstrate the widespread presence of ancient bacterial,

Mitoxantrone alters CD24/Siglec-10 expression in malignant brain tumor models

Medulloblastoma and glioblastoma are the most common malignant primary brain tumors in children and adults, respectively. Tumor-associated macrophages and microglia are key non-cancerous cell types in these tumors. These cells interact with CD24, a so called “don’t eat me signal” expressed on tumor cells, through Siglec-10, a receptor that contributes to immune evasion by promoting an immunosuppre

ClusterVAP : study protocol for multicentre proteomic endotyping of ventilator-associated pneumonia

INTRODUCTION: Ventilator-associated pneumonia (VAP) is the most frequent healthcare-associated infection in intensive care units and is associated with high morbidity and mortality. Current diagnostic criteria lack specificity, leading to misclassification and unnecessary antibiotic use. Identifying patient subgroups with a common pathophysiological basis (pneumoclusters) may distinguish true VAP

Exome analysis links kidney malformations to developmental disorders and reveals causal genes

Congenital anomalies of the kidneys and urinary tract (CAKUT) are developmental disorders that commonly cause pediatric chronic kidney disease and mortality. We examine here rare coding variants in 248 CAKUT trios and 1742 singleton CAKUT cases and compare them to 22,258 controls. Diagnostic and candidate diagnostic variants are detected in 14.1% of cases. We find a significant enrichment of rare

Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study

Background: Mammography screening programmes have been widely implemented across European countries over the past 40 years with the main aim to detect breast cancer earlier and thereby reduce breast cancer mortality. This study aimed to analyse and compare changes over time in breast cancer incidence, by stage at diagnosis, and breast cancer mortality across countries in relation to the timing of

Rapid imaging of intravenous gadolinium-based contrast agent (GBCA) entering ventricular cerebrospinal fluid (CSF) through the choroid plexus in healthy human subjects

BACKGROUND: Pathways for intravenously administered gadolinium-based-contrast-agents (GBCAs) entering cerebrospinal-fluid (CSF) circulation in the human brain are not well-understood. The blood-CSF-barrier (BCSFB) in choroid-plexus (CP) has long been hypothesized to be a main entry-point for intravenous-GBCAs into CSF. Most existing studies on this topic were performed in animals and human patient

Diagnostic accuracy of prenatal ultrasound in coarctation of aorta : systematic review and individual participant data meta-analysis

Objective: To determine the diagnostic accuracy of prenatal ultrasound in detecting coarctation of the aorta (CoA). Methods: An individual participant data meta-analysis was performed to report on the strength of association and diagnostic accuracy of different ultrasound signs in detecting CoA prenatally. MEDLINE, EMBASE and CINAHL were searched for studies published between January 2000 and Nove

Commissioning and operation of the Brazilian synchrotron light source

The Brazilian National Synchrotron Light Laboratory, LNLS, operates a 1.37 GeV electron storage ring with a 120 MeV injector Linac. Commissioning of the storage ring at low energy started on May 1996 and now, an year later, we can store 120 mA at 120 MeV and ramp more than 75 mA to 1.37 GeV. A summary of the latest commissioning results and a description of the present operational performance of t

Breast cancer hormone receptor levels and benefit from adjuvant tamoxifen in a randomized trial with long-term follow-up

BACKGROUND: Hormone receptor positivity predicts benefit from endocrine therapy but the knowledge about the long-term survival of patients with different tumor receptor levels is limited. In this study, we describe the 25 years outcome of tamoxifen (TAM) treated patients.PATIENTS AND METHODS: Between 1983 and 1992, a total of 4,610 postmenopausal patients with early-stage breast cancer were random

Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer

BACKGROUND: Capecitabine is an attractive radiosensitizer. In this study acute toxicity and surgical complications were evaluated in patients with locally advanced rectal cancer following total mesorectal excision (TME) after preoperative chemoradiotherapy (CRT) with capecitabine.METHODS: Between 2004 and 2008, consecutive patients with clinical tumour category (cT) 3-4 (with a threatened circumfe