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5-Hydroxytryptamine contracts human uterine artery smooth muscle predominantly via 5-HT2 receptors

Serotonergic receptors were classified in the isolated human uterine artery with intact endothelium, using agonists and antagonists for 5-hydroxytryptamine (5-HT) receptors. The efficacy for different agonists rated: alpha-methyl-5-HT (5-HT2) = 5-HT (non-selective) = 2-methyl-5-HT (5-HT3) >> sumatriptan (5-HT1), and the potency as: sumatriptan = 5-HT > 5-HT > alpha-methyl-5-HT > 2-methyl-5-HT. The

Naturally transformable Acinetobacter sp strain ADP1 belongs to the newly described species Acinetobacter baylyi

Genotypic and phenotypic analyses were carried out to clarify the taxonomic position of the naturally transformable Acinetobacter sp. strain ADP1. Transfer tDNA-PCR fingerprinting, 16S rRNA gene sequence analysis, and selective restriction fragment amplification (amplified fragment length polymorphism analysis) indicate that strain ADP1 and a second transformable strain, designated 93A2, are membe

Joseph Beuys : fett och filt : en forskningskritisk essä

Joseph Beuys. Fat and felt. A critical essay. The extremely singular materials fat and felt for use in art, have an entirely dominating role in a long series of Joseph Beuys’ (1921-1986) most important work. They are found both in single works of art as well as in installations and happenings from the beginning of the 1960s and up to the end of the artist’s life. This essay deals with the artist’

A hemolytic assay for the estimation of functional mannose-binding lectin levels in human serum

A simple assay was developed to estimate functional mannose-binding lectin (MBL) levels in serum based on the principle of yeast-induced bystander lysis of chicken erythrocytes (ChE). The assay is sensitive to inhibition by ethylene glycol bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) (which allows alternative pathway activation), ethylene diamine tetraacetic acid (EDTA), mannose,

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.

The extracellular matrix consists of structural macromolecules and other proteins with regulatory functions. An important family of the latter class of molecules found in most tissues is the small leucine-rich repeat proteins (SLRPs). We have previously shown that the SLRP fibromodulin binds directly to C1q and activates the classical pathway of complement. In the present study we further examine

Quantitative analysis of rat Ig (sub) classes binding to cell surface antigens

An indirect 125I-labeled protein A assay for detection of cell surface-bound rat immunoglobulins is presented. The assay is quantitative and rapid and detects as little as 1 ng of cell surface-bound Ig. It discriminates between antibodies belonging to different IgG subclasses, IgM and IgA. We describe the production and specificity control of the reagents used and show that the test can be used fo

Changes in high-frequency QRS components are more sensitive than ST segment deviation for detecting acute coronary artery occlusion

OBJECTIVES This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion. BACKGROUND Previous studies have shown decreased HF-QRS in the frequency range of 150–

Effects of nitrogen deposition on the growth, metabolism and activity of ectomycorrhizal fungi

Popular Abstract in Swedish Nästan alla träd i våra skogar lever i samspel (symbios) med svampar. Många av dessa är ”vanliga” svampar, sådana som vi är vana vid att se och plocka i naturen, (exempelvis soppar, kremlor, riskor, flugsvampar och kantareller) men det finns också de som inte bildar fruktkroppar, eller har fruktkroppar som vi inte ser. Fruktkropparna, de som kan hamna i svampkorgen, är Elevated nitrogen (N) deposition is an environmental problem that can affect plants and microorganisms, which are vital for the terrestrial N and carbon (C) cycles. This thesis has investigated the response of ectomycorrhizal fungi (EMF) to increased N deposition. Ectomycorrhizal fungi form mutualistic interactions with the roots of woody plants, including almost all boreal and temperate forests

Tehnology Shift and Long term Growth in Regions

Abstract The overarching aim of this paper is to investigate the importance of technological shifts and national macroeconomic preconditions for long term growth and structural transformation in various regions in a national regional system. Intrinsic to this, the issue and origin of divergence and convergence coming in repetitive waves in regional systems will be discussed as a possible contribut

On the concept of "integration"

There are a number of interpretations of the concept “integration” in Product Development (PD). Different sources tend to use different terminologies for describing the same phenomenon of integration, or use the same term for different purposes. This paper strives to capture the essence of the concept of “integration” within a product development project by looking for what is integrated and how i

Minimal Solutions for Panoramic Stitching with Radial Distortion

This paper presents a solution to panoramic image stitching of two images with co- inciding optical centers, but unknown focal length and radial distortion. The algorithm operates with a minimal set of corresponding points (three) which means that it is well suited for use in any RANSAC style algorithm for simultaneous estimation of geometry and outlier rejection. Compared to a previous method for

Critical science with the largest telescopes: science drivers for a 100m ground-based optical-IR telescope

Extremely large filled-aperture ground-based optical-IR telescopes, or ELTs, ranging from 20 to 100m in diameter, are now being proposed. The all-important choice of the aperture must clearly be driven by the potential science offered. We here highlight science goals from the Leiden Workshop in May 2001 suggesting that for certain critical observations the largest possible aperture - assumed to be

Cooperation in Planning of Production and Working Environments Supported by Computer Graphics

A methodology for studying change processes in working life combining computer-aided planning and cooperation in project groups is evaluated. The methodology is applied and studied in a planning workshop with representatives from manufacturing industries—managers, production engineers, supervisors as well as shop floor workers—and from health-and-safety agencies utilizing the methodology for plann

Relative economic backwardness and catching up: lessons from history, implications for development thinking

This chapter expands on three main topics. First, it is argued that the economic historical perspective may contribute to our understanding of present day development processes. Instead of advocating a one-size-fits-all model, an analytical framework is offered based on common traits from diverse examples. Second, the importance of agricultural change on the road towards sustained economic growth

The Doctrine of Precontractual Liability

Under the principle of freedom of contract, when two parties begin contract negotiations, they are under no obligation to actually arrive at an agreement and each one carries the risk for its own expenses and losses caused by the negotiations. However, even if the main rule says that each party bears the costs it might have incurred during the negotiations, if the parties do not reach an agreement