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This thesis considers methods for synthesis of linear quadratic controllers for large-scale, interconnected systems. Conventional methods that solve the linear quadratic control problem are only applicable to systems with moderate size, due to the rapid increase in both computational time and memory requirements as the system size increases. The methods presented in this thesis show a much slower
This doctoral thesis comprises a critical edition of a previously unpublished manuscript from the late seventeenth century, which is housed in Lund University Library. The manuscript consists of copies of eighty-eight letters and other documents in Latin. The originals were, in most cases, written by country vicars from Scania, a Swedish province that until 1658 was part of Denmark. The identity o
In this study, we sought evidence for alpha-synuclein (ASYN) expression in oligodendrocytes, as a possible endogenous source of ASYN to explain its presence in glial inclusions found in multiple system atrophy (MSA) and Parkinson's disease (PD). We identified ASYN in oligodendrocyte lineage progenitors isolated from the rodent brain, in oligodendrocytes generated from embryonic stem cells, and in
Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin
In this thesis I have discussed the possibility of building a stable and long-lasting peace in a state whose society is considered to be deeply divided ? Bosnia and Herzegovina. The main question to be answered by this study was Which factors facilitate and which factors obstruct stable and long-lasting peace in a deeply divided society? I have examined the post-war constitutional design of Bosnia
To improve the results of Enterprise Systems (ES) implementation projects, new or revised implementation methodologies are introduced by ES vendors. Yet, the innovation and adoption of implementation methodologies (IM), which are computer-based and incorporate both project management and functional components, can be problematic. The purpose of this paper is to describe and explain the adoption of
Purpose - H2O, CO2 and CO are three main species in combustion systems which have high volume fractions. In addition, soot has strong absorption in the infrared band. Thus, H2O, CO2, CO and soot may take important roles in radiative heat transfer. To provide calculations with high accuracy, all of the participating media should be considered non-gray media. Thus, the purpose of this paper is to st
Road Safety Audits (RSA) and Road Safety Inspections (RSI) are effective means of Road Infrastructure Safety Management. They are preventive tools, consisting of systematic, safety assessments, carried out by trained, independent safety expert teams, resulting in a formal report on detected road hazards and safety issues, requiring a formal response by the relevant road authority. Yet, current reg
Stars near the Sun oscillate both horizontally and vertically. In a previous paper by Binney it was assumed that the coupling between these motions can be modelled by determining the horizontal motion without reference to the vertical motion, and recovering the coupling between the motions by assuming that the vertical action is adiabatically conserved as the star oscillates horizontally. Here, we
Present debates suppose a close linkage between economic, social, and environmental sustainability and suggest that individual wellbeing and living standards need to be understood as directly linked to environmental concerns. Because social movements are often seen as an avant-garde in pushing for change, this article analyzes climate protesters' support for three key frames in current periods of
Gebel el-Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia; from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, reGebel el Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia: from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, re
Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat
Purpose - The dimple is adopted into a double wall cooling structure which is widely used in hot gas components to increase the heat transfer effects with relatively low pressure drop penalty. The purpose of this paper is to study the effect of dimple depth and dimple diameter on the target surface heat transfer and the inlet to outlet friction factor. Design/methodology/approach - The study is ca
The discovery that variants in the melatonin receptor 2 (MTNR1B) gene were associated with glucose levels, insulin secretion, and risk for type 2 diabetes (T2D) in genome-wide association studies (GWAS) reinforced the previously suggested link between glucose homeostasis and circadian rhythmicity. Diurnal secretion of melatonin has reported to be altered in people with diabetes and rodent models o
Type 2 diabetes has become a leading health problem throughout the world. The escalating epidemic of type 2 diabetes is believed to result from a collision between inherent biological susceptibilities (genotypes) and a shift toward dietary habits and lifestyle that promote obesity over the past several decades; the transition from “traditional” to modern “obesogenic” lifestyles is characterized by
Chromosomal rearrangements (e.g., fusions/fissions) have the potential to drive speciation. However, their accumulation in a population is generally viewed as unlikely, because chromosomal heterozygosity should lead to meiotic problems and aneuploid gametes. Canonical meiosis involves segregation of homologous chromosomes in meiosis I and sister chromatid segregation during meiosis II. In organism
